The best food sources for phosphorus are meat, dairy, oily fish, and seeds. The daily amount of phosphorus needed is defined in several different ways. Side Effects Phosphorus is so readily available in the food supply, so deficiency is rare. Although not all of these side effects may occur, if they do occur they may need medical attention. In the past, there was a concern that consuming too much phosphate could throw off this fine-tuned balance, drawing calcium from bone and increasing the risk of osteoporosis (bone mineral loss). However, UTIs are more common in women with hypercalcemia (abnormally high calcium) as the increased urinary calcium promoted bacterial growth. You can also get too much phosphorus, a condition called hyperphosphatemia, if you take too much of the supplement phosphate. Never used expired supplements or supplements that are discolored or deteriorating, no matter the "use-by" date. Phosphate supplements are vulnerable to extreme heat, humidity, and ultraviolet (UV) radiation. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. You need to obtain it from food and, if needed, a dietary supplement (phosphate is the drug form of phosphorus). The best dietary sources of phosphorus include dairy products, meat, poultry, fish, and cereal products. Drug information provided by: IBM Micromedex. J Biol Chem. James Myhre is an American journalist and HIV educator. Due to this, phosphate is rarely taken on its own but rather as part of a multivitamin/mineral supplement. But stay on the safe side and look for supplements made from plants. Phosphate supplements may help reverse this risk by binding with free-circulating calcium and clearing it in the stool. Phosphorus is one of 16 essential minerals. Call your doctor for medical advice about side effects. Phosphate may interact with some pharmaceutical and over-the-counter medications. Trautvetter, U.; Distcheid, B.; Jahreis, G. et al. Arno Kroner, DAOM, LAc, is a board-certified acupuncturist, as well as an herbalist and integrative medicine doctor. A 2015 study published in the Nutrition Journal proved this wasn't the case. Phosphorus in supplements is usually in the form of phosphate salts (e.g., dipotassium phosphate or disodium phosphate) or phospholipids (e.g., phosphatidylcholine or phosphatidylserine). Allergies to phosphate are rare, but it's still important to call your doctor or seek emergency care if you experience rash, hives, shortness of breath, rapid heartbeat, or swelling of the face, throat, or tongue after taking a phosphate supplement. For phosphate supplement: Adults—One or two tablets four times a day. Hyperphosphatemia is typically accompanied by low levels of calcium which may result in muscle cramps, muscle spasms, and perioral (by the mouth) numbness or tingling. Vitamin B6 is a natural substance and the body needs it to produce chemical reactions. Check with your doctor as soon as possible if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Where to Find It Phosphorus is highest in protein-rich foods and cereal grains. To ensure quality and safety, only buy supplements that have been voluntarily submitted for testing by an independent certifying body like the United States Pharmacopeia (USP), ConsumerLab, of NSF International. Supplements can help you meet your daily needs if your diet isn't quite cutting it. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Unless you have a medical condition that requires supplementation, like alcoholism or chronic obstructive pulmonary disease (COPD), you would be better served to eat a healthy, balanced diet rich in macro and trace nutrients. Phosphate supplement may contain a large amount of sodium. Along with its needed effects, a medicine may cause some unwanted effects. However, too much dicalcium phosphate, or dicalcium phosphate taken in conjunction … Phosphorus is a mineral that’s found in the bones and processed by the kidneys. Dicalcium phosphate is a calcium supplement commonly found in prepared breakfast cereals, in pharmaceuticals as an inert ingredient to bind tablets, and in toothpastes. Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Phosphorus is an essential mineral found in every cell of the human body. See our safe care and visitor guidelines, plus trusted coronavirus information. He operates a private practice in Santa Monica, California. Allergies to phosphate are rare, but it's still important to call your doctor or seek emergency care if you experience rash, hives, shortness of breath, rapid heartbeat, or swelling of the face, throat, or tongue after taking a phosphate supplement. Some, however, still suggest that the supplement should be approached with caution, particularly for people with pre … High doses can lead to headaches, nausea, dizziness, diarrhea, and vomiting. According to the current research, high doses of phosphate increase bone mass density (BMD) and bone mass content (BMC) while decreasing the risk of osteoporosis in adults with adequate calcium intake. It has long been presumed that doing so can help treat certain urinary tract infections or prevent the formation of kidney stones. The takeaway Phosphorus is … How to Use It Phosphorus supplements are unnecessary. Upset stomach or throwing up. For U.S.— Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. calcium or zinc, may cause side effects. Injections are generally indicated when the blood phosphorus level drops below .4 millimoles per liter (mmol/L). Side Effects. Most people get all the phosphorus they need from diet. Side Effects. Phosphate supplements are sometimes used to make the urine more acidic. Call your doctor for medical advice about side effects. Brunelli, S. and Goldfarb, S. Hypophosphatemia: Clinical Consequences and Management. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. This drug may be used in people who cannot get enough phosphorus from their diets. These could be signs of potentially life-threatening, whole-body reaction known as anaphylaxis. Phosphate supplement side effects. Dietary supplements are largely unregulated in the United States and are not subject to the rigorous testing and research that pharmaceutical drugs are. However, certain diets and health conditions can cause phosphorus … Phosphate is also included in many multivitamin/mineral supplements as well as co-formulated supplements designed specifically for bone health. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Phosphate Supplement (Oral Route, Parenteral Route), FREE book offer – Mayo Clinic Health Letter, decrease in amount of urine or in frequency of urination, numbness, tingling, pain, or weakness in hands or feet, shortness of breath or troubled breathing. Since the kidneys are less able to clear phosphate from the body, the mineral may accumulate and lead to hyperphosphatemia (excessively high phosphorus levels). 2007;18(7):1999-2003; DOI: 10.1681/ASN.2007020143. Talk with your physician before taking phosphorus supplements if … (1997) Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Doing so prevents excess calcium from being deposited in blood vessels, which can increase the risk of atherosclerosis (hardening of the arteries). The rest is freely circulating in the bloodstream to facilitate other biological functions. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Dipotassium phosphate is declared “generally recognized as safe (GRAS)” by the U.S. Food and Drug Administration (FDA). Calcium and Phosphate Metabolism, Blood Lipids and Intestinal Sterols in Human Intervention Studies Using Different Sources of Phosphate as Supplements—Pooled Results and Literature Search. JASN. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Beyond the prevention or treatment of phosphorus deficiency, a phosphate supplement may offer specific health benefits, particularly in older adults and people prone to urinary tract infections (UTIs). It is the second most abundant mineral next to calcium, accounting for roughly 1 percent of your total body weight. These side effects may go away during treatment as your body adjusts to the medicine. Foods especially rich in phosphorus include: Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Phosphorus is also considered a macromineral (alongside calcium, sodium, magnesium, potassium, chloride, and sulfur) in that you need more of it than trace minerals like iron and zinc. Phosphorus supplements might also help with bone restoration and treating excessive levels of calcium in the body due to overactive parathyroid glands. Applies to potassium phosphate: intravenous solution. This content does not have an Arabic version. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Side Effects of P5P. Excess phosphorus can also affect urine acidity and lead to the dislodgement of a previously undiagnosed kidney stone. As a supplement, P-5-P is promoted to deliver greater benefits with fewer side effects, but there’s no clinical evidence to back this up. People almost never suffer from too much Vitamin B6 from food, but they can get too much of it in supplement form if it’s taken for too long . It is also believed to enhance athletic performance and strength, although there is little clinical evidence to support this claim. Although not all of these side effects may occur, … Excessively high levels of phosphorus in the blood, although rare, can combine with calcium to form deposits in soft tissues, such as muscle. Products typically provide 10% or less of the DV for phosphorus, but … These are minerals that the body needs to function normally. DOI: 10.1074/jbc.M115.645812. Dicalcium Phosphate Side Effects . By using Verywell Health, you accept our, Phytic Acid: Benefits, Side Effects, Dosage, and Interactions, Watch These Nutrients If You Have Diabetes-Related Kidney Disease, What You Need to Know About Calcium and Vitamin D Supplements, X-linked Hypophosphatemia: Symptoms, Causes, Diagnosis, and Treatment, Lactase supplements can help those with lactose intolerance, Food Nutrition Board of the Institute of Medicine, people in intensive care units (up to 33.9 percent), people involved in major trauma, such as a severe burn (75 percent), children zero to six months: 100 milligrams per day (mg/day), adolescents and teens nine to 18 years: 1,250 mg/day, pregnant or lactating women 18 and under: 1,250 mg/day, pregnant or lactating women over 18: 700 mg/day, Pumpkin or squash seeds: 676 mg per 1/4-cup serving, Sunflower sees: 343 mg per 1/4-cup serving, Canned sardines in oil: 363 mg per 2.5-ounce serving, Hard cheese: 302 mg per 1.5-ounce serving, Lentils (cooked): 264 mg per 3/4-cup serving, Canned salmon: 247 mg per 2.5-ounce serving, Canned tuna in water: 104 mg per 2.5-ounce serving. Drug information provided by: IBM Micromedex. If you have any questions about this, check with your health care professional. Therefore, the quality can vary—sometimes significantly. This is not a complete list of side effects and others may occur. All rights reserved. it is more associated with the failure to clear phosphorus from the body rather than with the use of phosphate supplements. In fact, 85 percent of the phosphorus found in the body resides in … Any excess phosphate in the blood is excreted either in urine or stool. Along with its needed effects, a medicine may cause some unwanted effects. 2015;14:28. Find everything you need to know about Potassium Phosphate, including what it is used for, warnings, reviews, side effects, and interactions. ... Pu-erh Tea: Benefits, Dosage, Side Effects… Find everything you need to know about Potassium Phosphate And Sodium Phosphate (PHOS-Nak), including what it is used for, warnings, reviews, side effects… Thank you, {{}}, for signing up. In addition, individuals who suffer from Addison's disease or disorders of the thyroid, lung and liver may be more likely to accumulate a high concentration of phosphorus in their blood if they take phosphorus supplements. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Phosphorus supports healthy nerve function and the contraction of all your body’s muscles, including the heart. These could be signs of potentially life-threatening, whole-body reaction known as anaphylaxis. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Belly pain. Primary information, health benefits, side effects, usage, and other important details Creatinol O-Phosphate (COP) is a synthetic analogue of creatine that was created as a cardioprotective drug, and it appears to be helpful against arrythmia and aid the integrity of cardiac tissue following injections of up to three grams. Copyright © 2020 IBM Watson Health. Phosphorus also regulates how much calcium is in the body and how much is excreted in urine. Portions of this document last updated: Oct. 01, 2020. Phosphorus works with calcium to help build healthy bone and teeth. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Read our, Medically reviewed by Arno Kroner, DAOM, LAc, Medically reviewed by Douglas A. Nelson, MD, Medically reviewed by Richard N. Fogoros, MD, Medically reviewed by Ana Maria Kausel, MD, Medically reviewed by Jonathan B. Jassey, DO, Medically reviewed by Jonathan Cluett, MD, Verywell Health uses cookies to provide you with a great user experience. Calcium phosphate — which you find as tricalcium phosphate in supplements — contains close to 39 percent elemental calcium. ... didanosine, vitamins/minerals, and antacids. In some cases, separating the drug doses by two to four hours will help overcome the interaction. Approximately 85% of Phosphorus is found in your bones and teeth. What are the side effects and safety precautions of taking a phosphorus supplement? Phosphate supplements are considered safe if taken as prescribed. Kidney stones composed of calcium oxalate develop when the urine pH is less than 6.0 (meaning that it is acidic). Phosphorus isn’t commonly supplemented, even though it’s the second most plentiful mineral in our bodies, after calcium. Know Phosphorus uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Shields-Cutler, R.; Crowley, J.; Hung, C. et al. This content does not have an English version. Advertising revenue supports our not-for-profit mission. Applies to calcium phosphate, tribasic: oral tablet. Mayo Clinic does not endorse companies or products. Lee, A. and Cho, S. Association between phosphorus intake and bone health in the NHANES population. ... [OTC]) medicines and herbal or vitamin supplements. Doing so helps ensure that cells and tissues are properly maintained, repaired, and replaced as they age. Gastrointestinal. Dennis Sifris, MD, is an HIV specialist and Medical Director of LifeSense Disease Management. Related Links List Phosphorous Supplement 280 Mg-160 Mg-250 Mg Oral Powder Packet side effects by likelihood and severity. Nutrients. If you notice any other effects, check with your healthcare professional. People with chronic kidney disease may need to avoid phosphate supplements. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Injectable phosphate is sometimes used to treat severe hypophosphatemia. Bloating. Increasing the acidity with phosphate may only promote, rather than inhibit, their growth. All drugs may cause side effects. Phosphorus also plays a key role in metabolism (the conversion of calories and oxygen to energy), muscle contraction, heart rhythm, and the transmission of nerve signals. A phosphate supplement is typically used to prevent a phosphorus deficiency, a condition considered rare in the United States outside of certain high-risk groups. In others, a dose adjustment or drug substitution may be needed. Though this is not true with all stones. Phosphate supplements are available in tablet or capsule form under various brand names. ISBN-10: 0-309-06350-7ISBN-10: 0-309-06403-1. It is always best to store the supplements in their original light-resistant container in a cool, dry room. Although not all of these side effects may occur, if they do occur they may need medical attention. Doses tend to range from 50 milligrams (mg) to 100 mg. These side effects may go away during treatment as your body adjusts to the medicine. In addition, phosphorus additives are used in many soft drinks and packaged foods. Recent studies, however, suggest that this may not be the case. High doses can lead to headaches, nausea, dizziness, diarrhea, and vomiting. Along with its needed effects, potassium phosphate may cause some unwanted effects. Around 85 percent of phosphorus in the human body is stored in bone. According to Food Nutrition Board of the Institute of Medicine, the recommended dietary intake (RDI) of phosphorus from all sources varies by age and pregnancy status, as follows: Dosages exceeding 3,000 to 3,500 mg/day are generally considered excessive and may adversely affect the balance of macro and trace minerals in your blood. A deficiency of phosphorus is usually accompanied by hypophosphatemia, or low blood phosphate levels, which can affect every organ system of the body and may lead to muscle weakness, bone pain, fractures, seizures, and respiratory failure. Unlike certain micronutrients, the body cannot produce phosphorus on its own. According to a study from Harvard Medical School, phosphorus deficiency is most commonly seen in: Low phosphorus can also affect people with certain diseases or medical conditions, including Cushing's disease, hypothyroidism, parathyroid disease, vitamin D deficiency, and malnutrition. Most multiple vitamin-mineral supplements do not contain phosphorus for this reason. Phosphorus is used for Nutritional Deficiencies, Increased Blood Calcium Levels, Hyperparathyroidism etc. However, certain types of medical conditions can make your body inefficient at removing extra phosphorus from the blood, which can result in a condition called hyperphosphatemia. However, many people have no side effects or only have minor side effects. Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved. Although the main function of phosphorus is to build and maintain bones and teeth, it also plays a major role in the formation of DNA and RNA (the genetic building blocks of the body). DOI: 10.3390/nu10070936. Side effects include diarrhea and stomach cramps . Don’t take this supplement if you’re pregnant or nursing, and take only the recommended amount to prevent the following adverse side effects: red, itchy, irritated skin from continual skin contact; loss of appetite, nausea or vomiting; other gastrointestinal problems and frequent urination. You may report side effects to the FDA at 1-800-FDA-1088. Dipotassium Phosphate Side Effects. Pyridoxal 5 Phosphate Side Effects We can almost never get enough vitamin B6 from food, but we can get too much of it in supplement form if it’s taken for too long a period ( x ). Although not all of these side effects may occur, if they do occur they may need medical attention. Similarly, kidney stones composed of calcium phosphate tend to develop when the urine pH is over 7.2 (meaning that it is alkaline). But some supplements, like magnesium. 2018;10(7):936. Certain drugs may cause decreases in phosphorus levels in the blood, including: Other drugs may cause phosphorus levels to rise excessively, including: If you are being treated with any of these medications, you should not take phosphate supplements without first speaking with your doctor. The normal range is .87 to 1.52 mmol/L. Along with its needed effects, a medicine may cause some unwanted effects. Side effects from phosphorus intake are rare because healthy kidneys help remove extra phosphate from your body to keep your blood levels in balance. Excessive intake of phosphorus (or phosphate) supplements may worsen conditions such as heart disease, pancreatitis, rickets, osteomalacia (softening of bones), high blood pressure, and liver and kidney disease. Phosphorus supplements that contain sodium can cause edema in people with heart failure or cirrhosis. 2015;290:15949-60. According to a 2015 study in the Journal of Biochemical Chemistry, urine with a high pH (meaning that it is less acidic) exerted stronger antimicrobial effects compared to urine with low pH/high acidity. Phosphate injections are only given in a healthcare setting under the direction of a qualified specialist. What are some other side effects of Sodium Phosphates Tablets? Outside of severe kidney dysfunction, hyperphosphatemia is extremely rare. Side effects requiring immediate medical attention. Beyond this, it may potentially cause: Symptoms may include rash, itching, muscle cramps, spasms, bone or joint pain, or numbness and tingling around the mouth. Hypophosphatemia may also be caused by the overuse of diuretics (water pills) or phosphate-lowering drugs used during kidney dialysis. It is also water-soluble, meaning the body releases it in urine. DOI: 10.1186/s12937-015-0017-0. Phosphate supplements are considered safe if taken as prescribed. For Healthcare Professionals. This site complies with the HONcode standard for trustworthy health information: verify here. Other symp… All rights reserved. That’s because most diets are typically plentiful in phosphorus, and too much can be an issue. Washington, D.C.: National Academies Press (US). Nutrition J. You may report side effects to Health Canada at 1-866-234-2345. Pyridoxal phosphate or P-5-P is the active form of vitamin B6, a crucial nutrient for physical and mental health. The excessive intake of phosphate may interfere with the body's ability to use iron, calcium, magnesium, and zinc. Moreover, increased phosphate intake was not associated with toxicity. BENEFITS OF PHOSPHORUS: Phosphorus is the second most plentiful mineral in your body, making up 1% of your body weight. By lowering the pH (and increasing the acidity), phosphate may able to prevent kidney stones in high-risk individuals. Human Urinary Composition Controls Antibacterial Activity of Siderocalin. These minerals are converted in the body into calcium phosphate salts that stiffen and strengthen bones.

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